Recent Publications

  1. Curtis KJ, Coughlin TR, Mason, DE, Boerckel, JD, Niebur, GL, 2018 "Bone marrow mechanotransduction in porcine explants alters kinase activation and enhances trabecular bone formation in the absence of osteocyte signaling." Bone 107:78 - 87
  2. Coughlin TR, Romero-Moreno, R, Mason, D, Nystrom, L, Boerckel, JD, Niebur, GL, Littlepage, LE, 2018, "Bone: A Fertile soil for cancer metastasis." Current Drug Targets 18(11):1281 - 1295
  3. Metzger TA, Niebur GL. "Comparison of Solid and Fluid Constitutive Models of Bone Marrow During Trabecular Bone Compression." J. Biomech, 2016, 49:3596-3601
  4. Kreipke TC, Garrison JG, Easley J, Turner AS, Niebur GL. "The roles of architecture and estrogen depletion in microdamage risk in trabecular bone." J. Biomech, 2016, 49:3223-3229
  5. Thomas R. Coughlin, Jessica Schiavi, M. Alyssa Varsanik, Muriel Voisin, Evelyn Birmingham, Matthew G. Haugh, Laoise M. McNamara and Glen L. Niebur "Primary cilia expression in bone marrow in response to mechanical stimulation in explant bioreactor culture." European Cells and Materials, 2016, 32:111-22
  6. Thomas A. Metzger, Stephen A. Schwaner, Anthony J. LaNeve, Tyler C. Kreipke, Glen L. Niebur "Pressure and shear stress in trabecular bone marrow during whole bone loading." J Biomech, 2015, 48(12):3035-43
  7. Birmingham E, Niebur GL, McNamara LM, McHugh PE "An Experimental and Computational Investigation of Bone Formation in Mechanically Loaded Trabecular Bone Explants." Ann Biomed Eng, 2016, 44(4):1191-203
  8. Baumann AP, Aref MW, Turnbull TL, Robling AG, Niebur GL, Allen MR, Roeder RK "The sensitivity of nonlinear computational models of trabecular bone to tissue level constitutive model." Comput Methods Biomech Biomed Engin, 2016, 19(5):465-73
  9. Coughlin TR, Voisin M, Schaffler MB, Niebur GL, McNamara LM. "Primary Cilia Exist in a Small Fraction of Cells in Trabecular Bone and Marrow." Calcif Tissue Int, 2015, 96(1):65-72.
  10. Metzger TA, Kreipke TC, Vaughan TJ, McNamara L, Niebur GL. "The in situ Mechanics of Trabecular Bone Marrow: The Potential for Mechanobiological Response." J Biomech Eng, 2015, 137(1):011006
  11. Vaughan TJ, Voisin M, Niebur GL, McNamara L. "Multiscale Modelling of Trabecular Bone Marrow: Understanding the Micromechanical Environment of Mesenchymal Stem Cells during Osteoporosis." J Biomech Eng. 2015, 137(1):011003
  12. Birmingham EC, Kreipke TC, Dolan EB, Coughlin TR, Owens P, McNamara LM, Niebur GL, McHugh PE. 2014; "Mechanical Stimulation of Bone Marrow In Situ Induces Bone Formation in Trabecular Explants." Annals of Biomedical Engineering, 2015, 43(4):1036-50
  13. Birmingham EC, Kreipke TC, Dolan EB, Coughlin TR, Owens P, McNamara LM, Niebur GL, McHugh PE. 2014; "Mechanical Stimulation of Bone Marrow In Situ Induces Bone Formation in Trabecular Explants." Annals of Biomedical Engineering
  14. Metzger TA, Shudick JM, Seekell R, Zhu Y, Niebur GL. 2014; "Rheological behavior of fresh bone marrow and the effects of storage." J Mech Behav Biomed Mater. 40C:307-313.
  15. Kreipke TC, Rivera NC, Garrison JG, Easley JT, Turner AS, Niebur GL. 2014; "Alterations in trabecular bone microarchitecture in the ovine spine and distal femur following ovariectomy." J Biomech. 47:1918-1921
  16. Gargac JA, Turnbull TL, Roeder RK, Niebur GL, 2014; "A probabilistic damage model based on direct 3-D correlation of strain to damage formation following fatigue loading of rat femora." J Mech Behav Biomed Mater.30(2):234-43.
  17. Wu Z, LaNeve AJ, Niebur GL, 2013, "In vivo microdamage is an indicator of susceptibility to initiation and propagation of microdamage in human femoral trabecular bone." Bone, 55(1):208-15.
  18. Birmingham E, Grogan JA, Niebur GL, McNamara LM, McHugh PE, 2013, "Computational Modelling of the Mechanics of Trabecular Bone and Marrow Using Fluid Structure Interaction Techniques." Annals of Biomedical Engineering, 41(4):814-26
  19. Baumann AP, Deuerling JM, Rudy DJ, Niebur GL, Roeder RK, 2012 "The relative influence of apatite crystal orientations and intracortical porosity on the elastic anisotropy of human cortical bone." J of Biomech, 45:2743-2749
  20. Coughlin TR, Niebur GL, 2012, " Fluid Shear Stress in Trabecular Bone Marrow due to Low-Magnitude High-Frequency Vibration. " J Biomech, 45:2222-2229
  21. Birmingham E, Niebur GL, McHugh PE, Shaw G, Barry FP, McNamara LM, 2012, " Osteogenic differentiation of mesenchymal stem cells is regulated by osteocyte and osteoblast cells in a simplified bone niche. " European Cells and Materials, 23:13-27
    Highlighted as top story in Mesenchymal Cell News
  22. Wu, Z, Ovaert, TC, and Niebur, GL, 2012, " Viscoelastic properties of human cortical bone tissue depend on gender and modulus. " Journal of Orthopaedic Research, 30(5):693-9
  23. Shepherd TN, Zhang, J, Ovaert, TC, Niebur GL, 2011, " Direct comparison of nanoindentation and macroscopic measurements of bone viscoelasticity. " Journal of the Mechanical Behavior of Biomedical Materials 4(8):2055-62
  24. Garrison, JG, Gargac, JA, Niebur GL, 2011, " Shear strength and toughness of trabecular bone are more sensitive to density than damage. " Journal of Biomechanics 44(16):2747-54
    Commentary in BoneKeys
  25. Wu, Z, Baker, T, Ovaert, TC, and Niebur GL, 2011, " The effect of holding time on on nanoindentation measurements of creep in bone. " Journal of Biomechanics 44(6): 1066-72
  26. Shi X, Liu XS, Wang X, Guo XE, Niebur GL, 2010, " Type and orientation of yielded trabeculae during overloading of trabecular bone along orthogonal directions." Journal of Biomechanics, 43(13) pp2460-6
  27. Shi X, Liu XS, Wang X, Guo XE, Niebur GL, 2010, " Effects of trabecular type and orientation on microdamage susceptibility in trabecular bone. " Bone 46(5):1260.
  28. Korecki CL, Zinser G, Liu X, Siedler J, Welsh J, Niebur GL, 2009, " Effect of the Vitamin D Receptor on Bone Geometry and Strength During Gestation and Lactation in Mice. " Calcified Tissue International 85(5):405-11.

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